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Traumatic Life Events May Increases Breast Cancer Risk

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Many believe in the power of positive thinking, but what role does negativity play? Can pessimism, psychological distress, and traumatic life events affect your health? Yes, say Israeli researchers from Ben-Gurion University and the University of Haifa.

Study Methodology
In their study, recently published online in BMC Cancer, Prof. Ronit Peled, Orly Siboni Samocha, Ilana Shoham-Vardi, and Devora Carmi interviewed 622 women aged 25 to 45. Of those, 255 had been diagnosed with breast cancer. The control group was 367 women who did not have breast cancer or other malignant disease.

The women were all given a questionnaires designed to measure their level of psychological distress, and another which determined which negative life events the person had experienced, and at what age. Events categorized as "severe" included loss of a parent before twenty years of age, divorce of parents before twenty years of age, loss of a close relative and a loss of a spouse. The mild to moderate events studied were separation from a spouse, loss of a job, economic crisis, severe illness of a close relative, severe illness, and "other moderate event."

Results
The study found that the cancer patients reported higher levels of depression and less optimism than the control group. They were also more likely to have experienced multiple traumatic life events, though there was no connection found to specific life events.

The researchers concluded that "we can carefully say, that experiencing more than one meaningful life event (severe and/or mild to moderate) is a risk factor for breast cancer among young women. On the other hand, general feelings of happiness and optimism can play a protective role against the disease."

They recommend that "young women who suffered a loss in their early childhood, especially those exposed to a number of life events, should be considered as a risk group and be treated accordingly.

Limitations of the Study
Researchers wrote of a number of issues with the study which may have influenced theresults. Firstly, the response rate among cancer patients was low (only 25%), and the controls were not randomly selected. Also, since the patients were interviewed post-diagnosis (an average of 1 year later), it is possible that their negative outlook on life could be a result of, rather than a cause of, their disease. However it should be noted that while the women's mental state could be subjective, the number of traumatic events experienced is not.

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