The second important study on smoking and breast cancer was published in the British Medical Journal in March of 2011. The Woman's Health Initiative involved almost 80,000 women between the ages of 50 and 75, approximately 3,250 of whom were diagnosed with breast cancer during a ten-year period of regular check ups following the initial collection of health data. The women who participated in the study were broken up into four groups:
- Those who smoked
- Those who smoked at one time but had quit
- Those who had been exposed to second hand smoke for a significant period of time
- Those who have never smoked
The study showed that active smoking and extensive passive smoking were associated with a significantly increased risk of breast cancer in postmenopausal women. These results support the recent conclusions of top expert panels that breast cancer must be added to the list of target organs that are affected by tobacco smoke. Interestingly, earlier research has shown that smoking is associated with lower participation in mammography screening.
The findings of the study are summarized below:
- Women who developed breast cancer were less likely to have been non-smokers.
- Among lifetime non-smokers, 88.1% were exposed to passive smoking, and most women had multiple types of passing smoking exposure.
- There is an elevated risk of breast cancer in former smokers (9%) and current smokers (16%), particularly with a long smoking history that started at an early age.
- A 32% excess risk of breast cancer was associated with the most extensive exposure to passive smoking among women who never smoked.
- Women who developed breast cancer were slightly older than women who did not, but their body mass index was similar.
- Women who developed breast cancer were likely to be non-Hispanic white, more highly educated, with a history of taking hormone replacement therapy, a history of alcohol intake, and a family history of breast cancer.
The Evidence is In
These two important research studies would seem to indicate that smoking can now officially be listed as a risk factor for breast cancer. In addition, the second study also appears to establish a significant connection to breast cancer and second hand smoke, although this still needs to be explored further.
Get Help to Quit Smoking
Debate may well continue about the relative strength of smoking as a risk factor for breast cancer, especially when compared to other well-known risks. But given the firmly established links that exist between smoking and innumerable other serious health conditions, any lingering uncertainty over the smoking-breast cancer connection is hardly a reason for any woman to resist giving up this dangerous and addictive habit.
Visit Smokefree.gov, a website created by National Cancer Institute’s Tobacco Control Research Unit, for valuable information, tools and support that can help you quit smoking.


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